[Todos] Seminario DQIAQF / INQUIMAE. Miercoles 5 de junio - 13 hs.

[andrea en qi.fcen.uba.ar]

Seminario DQIAQF / INQUIMAE. Miercoles 5 de junio - 13 hs.
Aula de Seminarios -- 3er piso.

Título de la charla:
Multi-Parametric Surface Plasmon Resonance -- The new generation of SPR

Niko Granqvist
Senior Application Scientist. BioNavis Ltd

Resumen:
Multi-Parametric Surface Plasmon Resonance (MP-SPR) is a novel approach
to the half-a-century old optical phenomenon Surface Plasmon Resonance
(SPR). For the last 20 years SPR has been predominantly used for
biomolecular interaction analysis. MP-SPR broadens the application range
also to biophysical studies, such as measurements of absolute refractive
indices and formed layer thicknesses, and biomaterials studies, such as
ceramic and polymer coating characterizations and biocompatibility studies.

The MP-SPR method is a sensitive approach to measurements of biochemical
interactions with both self assembled and hydrogel-coated sensors. The
added functionality of MP-SPR allows also labeled SPR, which provides
superior signal-to-noise ratio compared to traditional SPR, as well as
unprecedented selectivity in the detection.

MP-SPR is based on an optical arrangement that enables measurements on a
number of sensor coatings that cannot be measured with traditional SPR.
Apart from traditional hydrogel based biosensor coatings, a wide range
of different sensor surfaces are also possible to use, such as different
metals (Au, Ag, Al, Cu, Pt), polymers (PS, PEO, PMMA, cellulose), and
ceramics (Al2O3, SiO2). This opens up new areas of applications of
optical biosensor research, like developing new cellulose based
point-of-care devices, solving challenges in drug-container interactions
and quick biocompatibility characterization of implant materials and
coatings.