[Todos] PROXIMO SEMINARIO

[Fernando V. Molina]

Martes 4 de diciembre - 12 hs

Aula de Seminarios del INQUIMAE, 3er piso Pab. II



Dr. Rafael Radi
Universidad de la República, Montevideo, Uruguay

"Nitración de Proteínas: Mecanismos Bioquímicos y Consecuencias Biológicas"





Breve CV:
Rafael Radi received his M.D. and Ph.D. 
(biochemistry) degrees from the Universidad de la 
República de Uruguay in 1988 and
1991, respectively. He has been visiting 
professor at the University of Alabama at 
Birmingham in the 1990s, and participated in the 
seminal discoveries that characterized the 
reactions of peroxynitrite with biomolecules and 
identified it as a cytotoxic intermediate. Radi 
currently holds the position of Full Professor 
and Chairman of the Department of Biochemistry in 
the Facultad de Medicina of the Universidad de la 
República de Uruguay and is a Howard Hughes 
International Research Scholar. He also holds 
appointments as First Level Researcher in Biology 
and Chemistry of the Uruguayan National Research 
System and as Honorary Professor of the 
Universities of Buenos Aires (Argentina) and 
Alabama at Birmingham. He was a fellow of the 
International Union of Biochemistry (1991), a 
Senior Fulbright Foreign Scholar (1998) and a Guggenheim Foundation
Fellow (2003–2004). He has been elected to The 
Academy of Sciences for the Developing World 
(TWAS) (2004), the Argentinean National Academy 
of Sciences (2004) and the Brazilian Academy of 
Sciences (2006). He is the current President of 
the Society for Free Radical Biology and Medicine 
(2007–2008). Radi was awarded the national prizes 
for research in biology (1996) and basic sciences 
(1999). He has published over 120 original 
research articles and 20 review articles.
He has lectured extensively at universities, 
research centres and laboratories worldwide. Radi 
is the most highly cited investigator in his 
country and one of the most cited in Latin 
America, with over 10,500 citations and an 
H-index of 49. His current research interests are 
the biochemistry of peroxynitrite, its effect in 
mitochondrial dysfunction and apoptosis, its role 
in disease states and the development and testing 
of peroxynitrite decomposition catalysts. In 
addition, Radi works on the redox biology of 
Trypanosoma cruzi, the causative agent of 
American trypanosomiasis, in the context of peroxynitrite-dependent
cytotoxic responses mediated by the host.
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