<html>
<body>
<br>
<div align="center"><font size=5 color="#0000FF"><b>Martes</font>
<font size=5> 4 de diciembre - 12 hs<br><br>
</b>Aula de Seminarios del INQUIMAE, 3er piso Pab. II <br><br>
<br><br>
</font><font size=6><b>Dr. Rafael Radi<br>
</font><font size=4><i>Universidad de la República, Montevideo,
Uruguay<br><br>
</i></font><font size=6>"</font><font size=5>Nitración de Proteínas:
Mecanismos Bioquímicos y Consecuencias
Biológicas</font><font size=6>"<br><br>
<br><br>
<br><br>
</b></font></div>
Breve CV:<br>
Rafael Radi received his M.D. and Ph.D. (biochemistry) degrees from the
Universidad de la República de Uruguay in 1988 and<br>
1991, respectively. He has been visiting professor at the University of
Alabama at Birmingham in the 1990s, and participated in the seminal
discoveries that characterized the reactions of peroxynitrite with
biomolecules and identified it as a cytotoxic intermediate. Radi
currently holds the position of Full Professor and Chairman of the
Department of Biochemistry in the Facultad de Medicina of the Universidad
de la República de Uruguay and is a Howard Hughes International Research
Scholar. He also holds appointments as First Level Researcher in Biology
and Chemistry of the Uruguayan National Research System and as Honorary
Professor of the Universities of Buenos Aires (Argentina) and Alabama at
Birmingham. He was a fellow of the International Union of Biochemistry
(1991), a Senior Fulbright Foreign Scholar (1998) and a Guggenheim
Foundation<br>
Fellow (2003–2004). He has been elected to The Academy of Sciences for
the Developing World (TWAS) (2004), the Argentinean National Academy of
Sciences (2004) and the Brazilian Academy of Sciences (2006). He is the
current President of the Society for Free Radical Biology and Medicine
(2007–2008). Radi was awarded the national prizes for research in biology
(1996) and basic sciences (1999). He has published over 120 original
research articles and 20 review articles.<br>
He has lectured extensively at universities, research centres and
laboratories worldwide. Radi is the most highly cited investigator in his
country and one of the most cited in Latin America, with over 10,500
citations and an H-index of 49. His current research interests are the
biochemistry of peroxynitrite, its effect in mitochondrial dysfunction
and apoptosis, its role in disease states and the development and testing
of peroxynitrite decomposition catalysts. In addition, Radi works on the
redox biology of <i>Trypanosoma cruzi</i>, the causative agent of
American trypanosomiasis, in the context of peroxynitrite-dependent<br>
cytotoxic responses mediated by the host. <br>
</body>
</html>