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<b>MARTES 16</b> de septiembre 12<b> hs</b>. en el aula de
seminarios<br><br>
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Seminarios conjuntos de los Dres Ligia Toro y Enrico Stefani <br><br>
Titulo: “Mitochondrial BKCa Channels”<br><br>
Resumen: The opening of mitochondrial BKCa channels (mitoBK) is known to
protect the heart from ischemic insult. In the seminar, we will discuss
recent advances in mitoBK molecular composition and import to
mitochondria, and its regulatory role in mitochondrial Ca2+ retention
capacity. Ligia Toro, PhD. Professor and Dorothy and Leonard Straus
Scholar Division of Molecular Medicine, Department of Anesthesiology, and
Department of Molecular & Medical Pharmacology Univeristy of
California, Los Angeles, USA Title: "Recent advances in
super-resolution microscopy" Summary: Resolution beyond the
diffraction limit of ~50 nm can be achieved with Stimulation Emission
Depletion Microscopy (STED) that is based in bringing to the ground state
photons in the periphery of the focal spot. One major limitation of STED
is photobleaching . In the seminar the following points will be
discussed: 1. A novel system with minimal photobleaching with two
super-resolution channels based on a fast resonant scanning mirror and an
ultra-fast photon counting system, 2. Mechanisms of photobleaching, 3.
Recent discoveries of non-linear optical properties of metal
nano-particles that can lead to a new super-resolution microscopy and 4.
Development of a machine learning approach for image analysis. Enrico
Stefani MD, PhD, Distinguished Professor of Anesthesiology and
Physiology, John Bartley Dillon Endowed Chair in Anesthesiology Dorothy
and Leonard Straus Scholar, Director, Super Resolution Imaging Center,
Associate Director, Cardiovascular Research Laboratories David Geffen
School of Medicine at UCLA<br><br>
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Host. ODU </body>
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