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<P class=MsoNormal style="TEXT-ALIGN: center" align=center><STRONG><SPAN
style="FONT-SIZE: 14pt; FONT-FAMILY: Verdana">Lunes 22 de marzo 13 <SPAN
class=spelle>hs</SPAN></SPAN></STRONG></P>
<P class=MsoNormal style="TEXT-ALIGN: center" align=center><STRONG><SPAN
style="FONT-FAMILY: Verdana"></SPAN></STRONG> </P>
<P class=MsoNormal style="TEXT-ALIGN: center" align=center><STRONG><SPAN
style="FONT-FAMILY: Verdana">Aula Seminarios INQUIMAE-DQIAQF</SPAN></STRONG></P>
<P class=MsoNormal style="TEXT-ALIGN: center" align=center><STRONG><SPAN
style="FONT-FAMILY: Verdana"> Ciudad Universitaria <SPAN
class=spelle>Pab</SPAN>. II Piso 3</SPAN></STRONG><STRONG><SPAN
style="FONT-FAMILY: Symbol">°</SPAN></STRONG></P>
<P class=MsoNormal style="TEXT-ALIGN: center" align=center><STRONG><EM><SPAN
lang=EN-US style="FONT-FAMILY: Verdana"><?XML:NAMESPACE PREFIX = O
/><O:P> </O:P></SPAN></EM></STRONG></P>
<P class=MsoNormal style="TEXT-ALIGN: center" align=center><SPAN lang=EN-US
style="FONT-FAMILY: Verdana"><EM><FONT size=4>"The toxicological Impact of
Nanoparticles"</FONT></EM></SPAN></P>
<P class=MsoNormal><SPAN lang=EN-US
style="FONT-FAMILY: Verdana"></SPAN> </P><SPAN lang=EN-US
style="FONT-FAMILY: Verdana">
<DIV align=center><FONT face="Times New Roman"><STRONG><EM>Dr. Roberta Brayner
(Associate Professor)</EM></STRONG></FONT></DIV>
<DIV align=center><FONT face="Times New Roman" size=1><EM>NANOMATERIALS
TEAM</EM></FONT></DIV>
<DIV align=center><FONT face="Times New Roman" size=1><EM>Université Paris
Diderot (Paris 7)</EM></FONT></DIV>
<DIV align=center><FONT face="Times New Roman" size=1><EM>Interfaces,
Traitements, Organisation et Dynamique des Systèmes -
ITODYS-CNRS</EM></FONT></DIV>
<DIV align=center><FONT size=2></FONT> </DIV>
<DIV align=left>
<P class=MsoNormal style="MARGIN: 0cm 0cm 0pt; TEXT-ALIGN: justify"><SPAN
lang=EN-US style="mso-ansi-language: EN-US">To produce unique products with
novel properties we need to manipulate materials at the nanoscale level. In the
word, man-made nanoparticles and materials are being rapidly produced in large
quantities and it was shown, in the past ten years that nanomaterials have
different toxicity profiles compared with larger particles because of their
small size and also their high reactivity. In this moment, the toxicological and
environmental effects of direct or indirect exposure to these manufactured
nanomaterials are not completely elucidated. The physico-chemistry is essential
to understanding the fate and behavior of nanoparticles in the environment, as
well as uptake and distribution within organisms, and the interactions of
nanoparticles with other pollutants. It has been reported that when the particle
size decreases, there is a tendency to increase the toxicity, even if the same
material is relatively inert in bulk form (e.g. SiO<SUB>2</SUB>, carbon black,
TiO<SUB>2</SUB>, ZnO). The nanoparticles, due to their nanoscale, shape and
consequently huge surface area, may interact more efficiently with biological
systems producing important toxicity. In addition, the surface area are directly
correlated to many others physico-chemical properties such as chemical
reactivity, surface adsorption ability, surface charge, etc. All these factors
strongly dominate nanotoxicological behavior <I>in vivo</I>. In addition, the
toxicological impact of nanoparticles depends also on the biological target
used. In this new multi-disciplinary field, there are many challenges ahead and
some controversies, but knowledge transfer from biology, toxicology, colloid
chemistry, as well as material and geological sciences, will enable to improve
(nano)ecotoxicology studies. The present work is focused on (i) the study of the
physico-chemical properties of some nanoparticles (TiO<SUB>2</SUB>, ZnO, CdS,
Fe, CeO<SUB>2</SUB>, carbon nanotubes) prepared without and with protective
agents before and after contact with the culture media and also (ii) the study
of the ecotoxic impact of these nanoparticles on microorganisms.<?xml:namespace
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