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<blockquote type=cite cite><br>
<br>
Hola a todos,<br>
Quería recordarles del seminario de mañana, y confirmar que el lugar de
encuentro será el aula 4 del Pab. II (en el entre-subsuelo del pabellon,
lado paradas de colectivos) a las 13hs.<br>
Los esperamos!<br>
<br>
Dra. Mariana Feld<br>
Laboratorio de Neurobiología de la Memoria<br>
Depto Fisiología, Biología Molecular y Celular<br>
Facultad de Ciencias Exactas y Naturales<br>
Universidad de Buenos Aires<br>
<br>
Tel: +54 11 4576-3348/3300 al 09 int 431<br>
Fax: +54 11 4576-3447<br>
<br>
<br>
<br>
<font face="Tahoma" size=2><b>De:</b> Mariana Feld
<mfeld@fbmc.fcen.uba.ar><br>
<b>Para:</b> Alejandro Schinder <aschinder@leloir.org.ar>;
vsanchez@fmed.uba.ar; dcalvo@dna.uba.ar; Fernanda Ceriani
<FCeriani@leloir.org.ar>; Gabo Mindlin
<gabo.mindlin@gmail.com>; djerusal@fmed.uba.ar;
jerusali@mail.retina.ar; gmurer@fmed.uba.ar; ekatz@dna.uba.ar;
hviola@fmed.uba.ar; FPitossi@leoir.org.ar; ingelmi@dna.uba.ar;
jpasquin@qb.ffyb.uba.ar; jmedina@fmed.uba.ar; mariuchu@gmail.com;
mca@mail.retina.ar; B. Silvano Zanutto <silvano@fi.uba.ar>; Silvina
Ponce Dawson <silvina@dfuba.df.uba.ar>; sgallardo@bl.fcen.uba.ar;
"odu@fbmc.fcen.uba.ar" <odu@fbmc.fcen.uba.ar><br>
<b>Enviado:</b> martes 24 de marzo de 2009, 0:03:55<br>
<b>Asunto:</b> Seminario IBRO (Seminarios Conjuntos DFBMC/IFIByNE)
Viernes 27/03- 13hs<br>
</font><br>
<font size=2>Por favor, difundir.<br>
</font><br>
<u>Seminarios DFBMC/IFIByNE 2009</u>:<br>
<br>
<font size=2><b>Esta semana nos visitará la Dra Marina Bentivoglio, de
la Facultad de Medicina dela Universidad de Verona y Secretaria
General de IBRO, </b>quien dará 2 charlas: un seminario sobre sus
trabajosde investigación, y al final todos aquellos que tengan interés
en las actividades de IBRO (cursos, escuelas, financiación de estadías,
etc.), ideas que proponer o problemas que discutir en relación a IBRO
estan invitados a una charla informal.<br>
</font><br>
<font size=2><b>Viernes 27/03</b> - 13hs - Lugar a confirmar en el
pabellón II de Ciudad Universitaria.<br>
</font><br>
<font size=2>Seminarios:<br>
</font><br>
<font size=2><b>Brain clocks, inflammation and ageing</b><br>
Marina Bentivoglio<br>
Department of Morphological and Biomedical Sciences, University of
Verona, Verona, Italy<br>
<br>
Life flows over time, the fourth dimension of life, which shapes our
days, months and years, and clocks tick in the brain to measure time. In
mammals, biological rhythms are controlled by the suprachiasmatic nuclei
(SCN) of the anterior hypothalamus which function as a master biological
clock. The SCN thus governs the sleep-wake cycle, as well as of
endogenous rhythms in behavioral, hormonal and immune functions. Other
neural cell groups act as “switches” of biological functions. For
example, orexin-containing neurons in the dorsolateral hypothalamus play
a key role in wake regulation and are involved in circuits underlying the
transition from sleep to wake. Despite the wealth of knowledge
accumulated in the last years on the regulation of the SCN and brain
“switches”, the effect exerted by inflammatory signalling on these
cell groups has been relatively neglected, though it can be implicated in
diverse pathological and physiological conditions. Paradigmatic is, in
this context, a severe neuroinflammatory condition represented by African
trypanosomiasis or sleeping sickness. This neglected parasitic disease,
which is fatal if uncured, is hallmarked in humans by alterations of the
sleep-wake cycle. Findings which implicate a dysregulation of brain
clock/s in experimental models of this disease will be discussed. On the
other hand, in the context of physiological conditions, a number of data
in the last years have pointed out that normal aging is hallmarked by
low-grade chronic inflammatory activity, with increased production of
proinflammatory cytokines peripherally and in the brain and decreased
anti-inflammatory mediators. A puzzling aspect of aging is represented by
the frequent dysregulation of endogenous biological rhythms, and
especially of the sleep/wake cycle, and data will be presented on
aging-related changes of brain clock/s. The talk will thus delineate an
itinerary of research focusing on neural-immune interactions in the brain
timing machinery.<br>
<br>
<br>
<br>
<b>The International Brain Research Organization (IBRO) and worldwide
neuroscience</b><br>
<br>
Marina Bentivoglio<br>
University of Verona, Verona, Italy; IBRO Secretary-General<br>
<br>
The talk will give some highlights of the activities of IBRO, the world
federation of neuroscience societies, associations, groups
(<a href="http://www.ibro.info">www.ibro.info</a>). IBRO, a non-profit
organization, was founded in 1960 (at the birth of the modern era of the
“neurosciences”) to facilitate communication among neuroscientists
worldwide and to promote scientific exchanges and training in brain
research. Since the 1990s IBRO has concentrated efforts and resources on
the promotion of the neurosciences (and especially the training and
networking of young investigators) in disadvantaged countries of the
world. Main IBRO programs will be presented and discussed, with emphasis
on the Latin American community of neuroscientists.<br>
<br>
<br>
Host: Mariana Feld<br>
<br>
Los esperamos!!<br>
<br>
Dra. Mariana Feld<br>
Laboratorio de Neurobiología de la Memoria<br>
Depto Fisiología, Biología Molecular y Celular<br>
Facultad de Ciencias Exactas y Naturales<br>
Universidad de Buenos Aires<br>
<br>
Tel: +54 11 4576-3348/3300 al 09 int 431<br>
Fax: +54 11 4576-3447 <br>
<br>
<br>
</font><br>
<br>
<br>
<br>
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<br>
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<br>
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<br>
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