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Les recuerdo:<br><br>
Lunes 3 de diciembre, 14.30hs<br><br>
<b>SEMINARIO DEL DEPARTAMENTO DE QUIMICA BIOLOGICA<br><br>
Título del Seminario</b>: <font face="arial" size=2>"Linking
alternative splicing defects to human diseases"<br><br>
</font><b>Expositor</b>:<font face="arial" size=2>Dr Emanuele Buratti
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<font face="arial" size=2>El Dr Emanuele Buratti es Investigador Senior
del staff del ICGEB-Trieste (International Centre for Genetic Engineering
and Biotechnology). Pertenece al Grupo Molecular Pathology dirigido por
el Prof. Francisco E. Baralle. <br>
Emanuele Buratti se dedica a estudiar los mecanismos de splicing y la
estructura secundaria del RNA asociadas a enfermedades. <br>
Sus ultimas publicaciones son:<br>
</font> <br>
<font face="verdana" size=2>Buratti E, Baralle FE. <br>
Multiple roles of TDP-43 in gene expression, splicing regulation, and
human disease. <br>
Front Biosci. 2008 Jan 1;13:867-78.<br>
</font> <br>
<font face="verdana" size=2>Buratti E, Dhir A, Lewandowska MA, Baralle
FE. <br>
RNA structure is a key regulatory element in pathological ATM and CFTR
pseudoexoninclusion events.<br>
Nucleic Acids Res. 2007;35(13):4369-83.<br>
</font> <br>
<font face="verdana" size=2>Buratti E, Stuani C, De Prato G, Baralle FE.
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SR protein-mediated inhibition of CFTR exon 9 inclusion:
molecularcharacterization of the intronic splicing silencer.<br>
Nucleic Acids Res. 2007;35(13):4359-68.<br>
</font> <br>
<font face="verdana" size=2>Buratti E, Chivers M, Královicová J, Romano
M, Baralle M, Krainer AR,Vorechovsky I. <br>
Aberrant 5' splice sites in human disease genes: mutation pattern,
nucleotidestructure and comparison of computational tools that predict
their utilization.Nucleic Acids Res. 2007;35(13):4250-63.<br><br>
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</font>Los esperamos el <b>lunes a las 14.30 hs</b> en el Aula del
Departamento. <br><br>
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