<html>
<body>
<br>
<div align="center"><font size=5><b>Lunes 28 de mayo - 13 hs<br>
</b>Aula de Seminarios INQUIMAE-DQIAQF (3º piso Pab. II) <br><br>
<br><br>
</font><font size=6><b>Dr. Randy Duran</b></font> <br>
<font size=4><b>Department of Chemistry<br>
University of Florida<br>
Gainesville, FL 32611<br><br>
<br>
</font><font size=5>"</font><font size=6>Interfacing Ion Channels to
Microelectronics: Comparing Single Channel Activities from Four
Systems</font><font size=5>"<br><br>
<br>
</b></font></div>
Abstract:<br>
As part of a project centered on functionally incorporating ion channels
in non-native and polymer- stabilized lipid bilayers, we are interested
in characterizing the ion translocation behavior of the resulting
assemblies. We have investigated several ion-channels with a view
towards using them in tethered bilayers over microelectronic devices for
eventual biosensor applications. The ion channel characteristics
and their functional incorporation in bilayers will be presented.
Single channel ion current fluctuations were measured by several methods
and these data will be discussed. Finally methods to tether the ion
channel/lipid bilayer assembly to solid state devices and protein-based
techniques for stabilization will be presented. <br>
<img src="cid:7.1.0.9.0.20070523170314.01f34e58@qi.fcen.uba.ar.0" width=338 height=215 alt="[]">
<br>
</body>
</html>