[Todos] Seminario IBRO (Seminarios Conjuntos DFBMC/IFIByNE) Viernes 27/03- 13hs
Paula Felman
pfelman en fbmc.fcen.uba.ar
Mie Mar 25 10:39:24 ART 2009
>
>Seminarios DFBMC/IFIByNE 2009:
>
>Esta semana nos visitará la Dra Marina Bentivoglio, de la Facultad de
>Medicina dela Universidad de Verona  y Secretaria General de IBRO, quien
>dará 2 charlas: un seminario sobre sus trabajosde investigación, y al
>final todos aquellos que tengan interés en las actividades de IBRO
>(cursos, escuelas, financiación de estadÃas, etc.), ideas que proponer o
>problemas que discutir en relación a IBRO estan invitados a una charla
>informal.
>
>Viernes 27/03 - 13hs - Lugar a confirmar en el pabellón II de Ciudad
>Universitaria.
>
>Seminarios:
>
>Brain clocks, inflammation and ageing
>Marina Bentivoglio
>Department of Morphological and Biomedical Sciences, University of Verona,
>Verona, Italy
>
>Life flows over time, the fourth dimension of life, which shapes our days,
>months and years, and clocks tick in the brain to measure time. In
>mammals, biological rhythms are controlled by the suprachiasmatic nuclei
>(SCN) of the anterior hypothalamus which function as a master biological
>clock. The SCN thus governs the sleep-wake cycle, as well as of endogenous
>rhythms in behavioral, hormonal and immune functions. Other neural cell
>groups act as “switches†of biological functions. For example,
>orexin-containing neurons in the dorsolateral hypothalamus play a key role
>in wake regulation and are involved in circuits underlying the transition
>from sleep to wake. Despite the wealth of knowledge accumulated in the
>last years on the regulation of the SCN and brain “switchesâ€, the
>effect exerted by inflammatory signalling on these cell groups has been
>relatively neglected, though it can be implicated in diverse pathological
>and physiological conditions. Paradigmatic is, in this context, a severe
>neuroinflammatory condition represented by African trypanosomiasis or
>sleeping sickness. This neglected parasitic disease, which is fatal if
>uncured, is hallmarked in humans by alterations of the sleep-wake cycle.
>Findings which implicate a dysregulation of brain clock/s in experimental
>models of this disease will be discussed. On the other hand, in the
>context of physiological conditions, a number of data in the last years
>have pointed out that normal aging is hallmarked by low-grade chronic
>inflammatory activity, with increased production of proinflammatory
>cytokines peripherally and in the brain and decreased anti-inflammatory
>mediators. A puzzling aspect of aging is represented by the frequent
>dysregulation of endogenous biological rhythms, and especially of the
>sleep/wake cycle, and data will be presented on aging-related changes of
>brain clock/s. The talk will thus delineate an itinerary of research
>focusing on neural-immune interactions in the brain timing machinery.
>
>
>
>The International Brain Research Organization (IBRO) and worldwide
>neuroscience
>
>Marina Bentivoglio
>University of Verona, Verona, Italy; IBRO Secretary-General
>
>The talk will give some highlights of the activities of IBRO, the world
>federation of neuroscience societies, associations, groups
>(<http://www.ibro.info>www.ibro.info). IBRO, a non-profit organization,
>was founded in 1960 (at the birth of the modern era of the
>“neurosciencesâ€) to facilitate communication among neuroscientists
>worldwide and to promote scientific exchanges and training in brain
>research. Since the 1990s IBRO has concentrated efforts and resources on
>the promotion of the neurosciences (and especially the training and
>networking of young investigators) in disadvantaged countries of the
>world. Main IBRO programs will be presented and discussed, with emphasis
>on the Latin American community of neuroscientists.
>
>
>Host: Mariana Feld
>Â
>Los esperamos!!
>
>Dra. Mariana Feld
>Laboratorio de NeurobiologÃa de la Memoria
>Depto FisiologÃa, BiologÃa Molecular y Celular
>Facultad de Ciencias Exactas y Naturales
>Universidad de Buenos Aires
>
>Tel: +54 11 4576-3348/3300 al 09 int 431
>Fax: +54 11 4576-3447
>
>
>
>
>Yahoo! Cocina
>Recetas prácticas y comida saludable
>Visitá http://ar.mujer.yahoo.com/cocina/
>
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